Laboratory of natural product

Our laboratory focuses mainly on application of different mass spectrometric methods together with many interdependent analytical tools in unique ways to address a specific clinical problem that is not sufficiently addressed by the existing automated platforms.We develop and optimize methods using one- and two-dimensional gas chromatography-mass spectrometry (GC and GCxGC-MS) for characterization of volatile metabolites/markers produced by cell cultures, tissues, fungi, insects and other biological samples such as human breath. Furthermore, we apply matrix-assisted laser desorption/ionization-mass spectrometry imaging (MALDI-MSI) methods for mapping of biomolecules in diverse biological samples such as tissues, insect cuticle, etc.

Research objectives

  • GC-MS and GCxGC-MS analyses of volatile compounds in clinical samples
  • GC-MS and GCxGC-MS analyses of volatile components produced by insects and fungi
  • MALDI-MSI of biological tissues

Collaborations

  • International Atomic Energy Agency, Austria
  • Max Planck Institute for Chemical Ecology, Germany
  • University of Debrecen, Hungary
  • Institute of Organic Chemistry and Biochemistry of the CAS, Czech Republic
  • St Anne’s University Hospital Brno-International Clinical Research Centre, Czech Republic
  • Institute of Animal Physiology and Genetics CAS, Czech Republic
  • Brno University of Technology, Czech Republic
  • Masaryk University, Czech Republic

Patents

  • Do Nascimento RR, Vaníčková L, Mendonça AL, Galindo FCA, Tavares RF, Da Silva CE, Ferreira LL, De Aquino NC, Santos JL. 2016. Formulações sintéticas com atividade de cairomônio a partir de compostos voláteis emitidos por frutos Psidium guajava (goiaba), eficazes no controle da mosca-da-fruta Sul Americana, Anastrepha fraterculus. Universidade Federal de Alagoas, Maceio Brazil. Patent No. BR 10 2016 003821 9. Patent deposited on: 23/02/2016
  • Do Nascimento RR, Vaníčková L, Mendonça AL, Ferreira LL, De Aquino NC, Tavares RF, Milet-Pinheiro P. 2015. Formulações com atividade de feromônio sexual, eficazes no controle da mosca-das-frutas Anastrepha fraterculus. Universidade Federal de Alagoas, Maceio Brazil. Patent No. BR 10 2015 016404 1. Patent deposited on: 08/07/2015
  • Pires EP, Mendonça AL, Santos RS, Vaníčková L,  Sant´Ana AEG, Do Nascimento RR. 2014. Composição com atividade feromonal e seu uso no controle da broca de frutos de Anonaceas. Universidade Federal de Alagoas, Maceio Brazil. Ptanet No. BR 10 2014 010066 0.




Ing. Lucie Pompeiano Vaníčková, PhD.

Head - Laboratory of natural product


Phone: 420 545 133 352
Address: ÚCB AF, Zemědělská 1, 61300 Brno - Budova D
Office: BA02N3012
E-mail: luci.vanickova@gmail.com

Team members

  • Ing. Kristýna Pavelicová
  • Ing. Kristýna Zemánková

Topics of Ph.D. theses

  • Optional topic